Benzenepropanoic acid, β-(acetylamino)-

Benzenepropanoic acid, β-(acetylamino)- - Names and Identifiers

Name	3-(acetylamino)-3-phenylpropanoic acid
Synonyms	N-Acetyl-DL-β-phenylalanine N-Acetyl-beta-phenyl-beta-alanine N-ACETYL-3-PHENYL-DL-BETA-ALANINE 3-Acetamido-3-phenylpropanoic acid 3-(acetylaMino)-3-phenylpropanoic acid 3-(acetylamino)-3-phenylpropanoic acid Benzenepropanoic acid, β-(acetylamino)- Benzenepropanoic acid, .beta.-(acetylamino)-
CAS	40638-98-0
InChI	InChI=1/C11H13NO3/c1-8(13)12-10(7-11(14)15)9-5-3-2-4-6-9/h2-6,10H,7H2,1H3,(H,12,13)(H,14,15)

Benzenepropanoic acid, β-(acetylamino)- - Physico-chemical Properties

Molecular Formula	C11H13NO3
Molar Mass	207.23
Density	1.197g/cm³
Boling Point	449.2°C at 760 mmHg
Flash Point	225.5°C
Vapor Presure	7.44E-09mmHg at 25°C
BRN	2726794
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.547

Benzenepropanoic acid, β-(acetylamino)- - Risk and Safety

WGK Germany	3
FLUKA BRAND F CODES	10

Benzenepropanoic acid, β-(acetylamino)- - Introduction

3-(acetylamino)-3-phenylpropanoic acid is an organic compound commonly abbreviated as AAPA. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: 3-(acetylamino)-3-phenylpropanoic acid is a white crystalline or crystalline powder.
-Solubility: soluble in alcohol, chloroform and ether and other organic solvents, slightly soluble in water.
-Melting point: approximately between 140-144°C.

Use:
-Chemical synthesis: 3-(acetylamino)-3-phenylpropanoic acid can be used to prepare other drugs or organic compounds.
-Drug research: Due to its structural characteristics, 3-(acetylamino)-3-phenylpropanoic acid is used in drug research and development.

Preparation Method:
A common synthesis method is to synthesize by the following reaction:
1. Acetanilide and dibutyl malonate were transesterified to obtain dibutyl 3-acetamido-3-phenylmalonate.
2. after acid hydrolysis, the ester group is converted into carboxylic acid group to obtain 3-(acetylamino)-3-phenylpropanoic acid.

Safety Information:
- 3-(acetylamino)-3-phenylpropanoic acid has no obvious safety risk under normal conditions of use.
-However, as a chemical substance, you should follow regular laboratory safety procedures, such as wearing protective glasses and gloves, and ensure that you operate under well-ventilated conditions.
-Avoid contact with strong oxidants during storage and handling.

Please note that the specific application and safety of 3-(acetylamino)-3-phenylpropanoic acid also needs to be evaluated according to the specific situation and the use environment, and the operation and handling according to the safety data sheet of the relevant chemical.

Last Update：2024-04-09 20:45:29